Growth hormone is produced by the pituitary gland, an important gland at the base of the brain that influences almost every part of the body. Growth hormone regulates body composition, body fluids, muscle and bone growth, and mental function. When an individual has a growth hormone deficiency, it means that their pituitary gland cannot make enough growth hormone for the body’s needs. This can result in a variety of medical problems; however, growth hormone replacement very often improves most symptoms of this condition.

• Central weight gain

• Difficulty to lose weight

• Anxiety and depression

• Dry skin

• Fatigue

• Not feeling as yourself

• A decrease in energy

• A decrease in endurance

• The desire to avoid social situations

Adults who have a growth hormone deficiency have an increased chance of developing abnormal body composition, increased risk of cardiovascular disease and diabetes, and reduced energy. In addition, fat tends to be packed on more easily, especially around the abdomen.

The deficiency causes decreased muscle strength and endurance to work out. Bones are also weaker, with an increased chance of developing osteoporosis later in life. Adults with growth hormone deficiency also experience a higher overall cholesterol level in blood.

• Head injury

• Stroke

• Infections to the brain

• Bleeding in the brain

• Under-active hypothalamic drive

• Damage to the pituitary gland and hypothalamus

• Tumor in the pituitary gland and hypothalamus

• Surgery or radiation to remove a tumor